Formulating for Sensitive Skin:Dipotassium Glycyrrhizate & Licochalcone A

Sensitive skin presents a particular challenge for cosmetic manufacturers. Consumers may experience dryness, visible redness, tightness or discomfort, but these symptoms do not necessarily share the same underlying cause.

As a result, sensitive-skin formulation requires more than adding a soothing ingredient to an existing skincare product.

The selection of surfactants, preservatives, emulsifiers and functional ingredients can all influence the tolerance of the finished formula.

Two licorice-derived ingredients worth considering in this context are dipotassium glycyrrhizate and licochalcone A.

Dipotassium Glycyrrhizate in Soothing Formulations

Dipotassium glycyrrhizate is a water-soluble derivative of glycyrrhizic acid, a constituent of licorice root.

It is widely used in cosmetics designed to provide soothing and skin-conditioning benefits. Its water solubility makes it convenient for incorporation into toners, aqueous serums, gels and emulsions.

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For formulators, this flexibility is particularly useful when developing lightweight products that need to accommodate several functional ingredients without compromising their sensory characteristics.

Dipotassium Glycyrrhizate can be considered for facial moisturizers, after-sun products and formulations intended for skin prone to visible redness.

Its actual performance and compatibility should be assessed in the finished product.

Licochalcone A and Redness-Focused Skincare

Licochalcone A is a naturally occurring chalcone associated with Glycyrrhiza inflata.

Research has investigated its antioxidant and anti-inflammatory activities, making it relevant to cosmetic products developed for skin exposed to environmental stressors.

Unlike water-soluble dipotassium glycyrrhizate, licochalcone A requires different incorporation considerations because of its limited water solubility.

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Formulators should pay attention to the selected raw material grade, solvent system and processing conditions.

For R&D teams developing redness-focused products, Licochalcone A offers a distinct ingredient option.

Combining Soothing Ingredients With Barrier Support

Soothing ingredients are only one component of a sensitive-skin formulation.

Moisturizing agents, appropriate lipids and a well-designed emulsion system can help address dryness and support the skin barrier.

The compatibility of active ingredients with the overall formulation is especially important when targeting consumers who report stinging or discomfort.

Product developers should also distinguish between evidence obtained from individual ingredients and clinical results from finished formulations.

A well-designed sensitive-skin product needs to balance efficacy, stability, sensory performance and tolerance throughout its intended period of use.

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